Tramautic Brain Injury (TBI)
The mission of the Lybrand lab is to develop cellular and molecular based strategies to regenerate functional brain tissue following injury. Specifically, we are interested in using stem cell technology to better understand novel mechanisms of brain trauma and build neural circuits to be regrown and reconnected.
Overview of our Research
The brain has a very limited capacity to regenerate itself. Following brain injury, for example traumatic brain injury (TBI) or stroke, there is a permanent loss of neural tissue, including neuronal and glial cell populations. We are working to build cortical tissue grafts derived from stem cells capable of reestablishing critical neural circuits damaged during brain injury. The Lybrand lab uses an integrative approach of: